Risk Factors

Changes in lipid levels are seen following HIV infection. In addition, dyslipidemia is associated with the use of certain ARVs. Further details are provided in the section on causes of dyslipidemia.

  • Sex and ethnicity may influence lipid effects of ARVs1
    • women and patients of black race may be more likely to develop increased low-density lipoprotein cholesterol (LDL-c) than men or people of other ethnicities
    • Hispanic patients may be more prone to triglyceride elevations

Potential exacerbating conditions for dyslipidemia include:2

Dyslipidemia may occur with or without metabolic syndrome, which in the general population is associated with an increased risk of cardiovascular events.1

Dyslipidemia is an important and potentially reversible risk factor for cardiovascular disease. Refer to the diagnostic tools section for more information. 


  1. Tungsiripat M, Aberg JA. Dyslipidemia in HIV patients. Cleve Clin J Med. 2005;72:1113–1120.
  2. Dubé MP, Stein JH, Aberg JA, et al. Guidelines for the Evaluation and Management of Dyslipidemia in Human Immunodeficiency Virus (HIV)–Infected Adults Receiving Antiretroviral Therapy: Recommendations of the HIV Medicine Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group. Clin Infect Dis. 2003;37:613–627.