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Renal Impairment – Glossary

Glossary

ACEI

angiotensin-converting enzyme inhibitors are a group of pharmaceutical agents used primarily in the treatment of hypertension and congestive heart failure.

ARB

angiotensin receptor blockers are a group of pharmaceutical agents which modulate the renin-angiotensin-aldosterone system.

ARF

acute renal failure.

CCB

calcium channel blockers are a class of drugs and natural substances that disrupt the movement of calcium through calcium channels.

CKD

chronic kidney disease.

eGFR

estimated glomerular filtration rate is used to measure kidney function and is calculated in the laboratory from the level of creatinine in the blood. A normal eGFR is around 100ml/min in young adults.

ESRD

end stage renal disease is severe kidney disease or chronic kidney failure that has reduced kidney function to 10 percent or less of normal, requiring the patient to have dialysis or a transplant in order to survive.

Fanconi Syndrome

disorder of the kidney tubules in which certain substances normally reabsorbed into the bloodstream by the kidneys are released into the urine instead.

GFR

glomerular filtration rate.

Glomerulonephritis

inflammation of the glomeruli of the kidney.

HIVAN

HIV-associated nephropathy refers to kidney disease developing in association with HIV infection.

MDRD-GFR

modification of diet in renal disease-glomerular filtration rate. An equation that provides an estimate of GFR in patients with impaired renal function.

Metabolic acidosis

low blood pH that can be a complication of severe kidney disease.

Nephritis

inflammation of the kidney.

Nephrolithiasis

presence of kidney stones.

Nephropathy

refers to damage to or diseases of the kidneys.

Pulmonary oedema

fluid accumulation in the lung tissue that can result from kidney failure, in which the body is unable to excrete fluid and leading to fluid build-up. In patients with advanced kidney disease dialysis may be required to remove excess body fluid.

RI

renal impairment.

UA/C

urine albumin/creatinine ratio.

UP/C

urine protein/creatinine ratio.