Signs and Symptoms

Signs and symptoms of thromboembolic disease can vary depending on the location of the thrombosis. 

Deep venous thrombosis (DVT):1

  • pain/tenderness
  • warmth
  • edema
  • erythema

Pulmonary embolism (PE):2

  • dyspnea
  • tachypnea
  • pleuritic chest pain
  • hemoptysis
  • cough
  • syncope
  • tachycardia

Brain embolism/stroke:3

  • numbness /weakness resulting in partial or complete paralysis of one side of the body
  • sudden loss of vision
  • dizziness
  • communication problems
  • problems with balance and coordination
  • difficulty swallowing
  • sudden, severe headache
  • unconsciousness 

Myocardial infarction:4

  • chest pain
  • dyspnea
  • diaphoresis
  • nausea and vomiting

Find out more about Diagnostic tools


  1. Turpie AGG. ABC of antithrombotic therapy. Venous thromboembolism: pathophysiology, clinical features, and prevention. BMJ. 2002;325:887–890.

  2. Stein PD, Beemath A, Matta F, et al: Clinical characteristics of patients with acute pulmonary embolism: Data from PIOPED II. Am J Med. 2007;120:(10):871–879. 
  3. Giraldo EA. Overview of Stroke (Cerebrovascular Accident). Merck Manual. 2007. 
  4. Warnica JW. Acute Coronary Syndromes. Merck Manual. 2007.